Multimodal imaging with hybrid semiconductor detectors Timepix for an experimental MRI-SPECT system
Autor
Rok
2013
Časopis
Journal of Instrumentation
Web
Obsah
An increasing number of clinical applications are being based on multimodal imaging
systems (MIS), including anatomical (CT, MRI) and functional (PET, SPECT) techniques to
provide complex information in a single image. CT with one of the scintigraphic methods (PET or
SPECT) is nowadays a combination of choice for clinical practice and it is mostly used in cardiography
and tumour diagnostics. Combination with MRI is also being implemented as no radiation
dose is imparted to the patient and it is possible to gain higher structural resolution of soft tissues
(brain imaging). A major disadvantage of such systems is inability to operate scintillators with photomultipliers
(used for detection of g rays) in presence of high magnetic fields. In this work we
present the application of the semiconductor pixel detector for SPECT method in combination with
MR imaging. We propose a novel approach based on MRI compatible setup with CdTe pixel sensor
Timepix and non-conductive collimator. Measurements were performed on high proton-density
(PD) phantom (1H) with an embedded radioisotopic source inside the shielded RF coil by MRI animal
scanner (4.7 T). Our results pave the way for a combined MRI-SPECT system. The project
was performed in the framework of the Medipix Collaboration.
KEYWORDS: Gamma detectors (scintillators, CZT, HPG, HgI etc); Gamma camera, SPECT, PET
PET/CT, coronary CT angiography (CTA); Pixelated detectors and associated VLSI electronics;
Hybrid detectors
Granty
Příklad citace článku:
J. Zajíček, J. Jakůbek, M. Burian, M. Vobecký, A. Fauler, M. Fiederle, A. Zwerger, "Multimodal imaging with hybrid semiconductor detectors Timepix for an experimental MRI-SPECT system", Journal of Instrumentation (2013)